Isotopically Labeled Compounds
Medchemexpress LLC Nonan-1-ol-d19 | 349553-86-2 | 98.0% | 163.37 | 25 MG
Nonan-1-ol-d19 is a deuterium-labeled Nonan-1-ol. Stable heavy isotopes of hydrogen, carbon, and other elements, such as deuterium, have been incorporated into drug molecules for use as tracers in drug development and to study their impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Glutamine-5-13C | 159680-32-7 | 147.14 | 5 MG
L-Glutamine-5-13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid found abundantly throughout the body and is involved in many metabolic processes. It provides a source of carbons for oxidation in some cells. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during drug development. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes used as tracers for quantitation during drug development.
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-Mannose-13C | 70849-31-9 | 181.15 | 50 MG
D-Mannose-13C is the 13C labeled D-Mannose. D-Mannose is a carbohydrate that plays an important role in human metabolism, especially in the glycosylation of specific proteins.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
![Revvity Health Sciences Inc dTTP, [α-<sup>32</sup>P]- 3000Ci/mmol 10mCi/ml EasyTide, 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502809713.jpg-250.jpg)
Revvity Health Sciences Inc dTTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 250 µCi
dTTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 250 µCi
Medchemexpress LLC L-Leucine-d2 | 362049-59-0 | MFCD01861592 | 133.19 | 5 MG
L-Leucine-d2 is the deuterium-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) known to activate the mTOR signaling pathway. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer in quantitative analysis
- Functions as an internal standard for various analytical methods
- Activates the mTOR signaling pathway
- Potential to affect pharmacokinetic and metabolic profiles
Medchemexpress LLC Palmitic acid-d31 | 39756-30-4 | 287.62 | 250 MG
Palmitic acid-d31 is the deuterium labeled Palmitic acid, a long-chain saturated fatty acid commonly found in both animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. It can be used as a tracer and as an internal standard for quantitative analysis.
- Deuterium labeled palmitic acid.
- Long-chain saturated fatty acid.
- Found in both animals and plants.
- Can induce expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Tyrosine-d3 | 71939-39-4 | 184.21 | 1 MG
L-Tyrosine-d3 is a deuterium-labeled form of L-Tyrosine, a non-essential amino acid. It is designed for research applications, including use as a tracer and internal standard.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC (E)-2,3',4,5'-tetramethoxystilbene | 24144-92-1 | 99.4% | 300.35 | 1 ML
TMS ((E)-2,3′,4,5′-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. It shows a lesser inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 μM). This methylated derivative of resveratrol possesses anti-cancer activity.
- Selective and competitive CYP1B1 inhibitor
- Possesses anti-cancer activity
- IC50 for CYP1B1 is 6 nM
- IC50 for CYP1A1 is 300 nM
- IC50 for CYP1A2 is 3.1 μM
Cayman Chemical trns-Resveratrol-d4 100ug
An internal standard for the quantification of trans-resveratrol by GC- or LC-MS
Medchemexpress LLC Isovaleric acid-d2 | 95927-02-9 | 99.5% | 104.14 | 50 MG
Isovaleric acid-d2 is the deuterium labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and is known to affect neonatal death and possible Jamaican vomiting sickness in humans. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes have been incorporated into drug molecules largely as tracers for quantitation during the drug development process, and deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Stable isotope-labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs due to deuteration
- High purity
Medchemexpress LLC Tri-p-tolylamine-d21 | 201944-90-3 | 98.2% | 308.53 | 5 MG
Tri-p-tolylamine-d21 is the deuterium labeled Tri-p-tolylamine. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Revvity Health Sciences Inc 14C Extended Range Quenched Standards, 20 mL Vial
14C Extended Range Quenched Standards, 20 mL Vial
Medchemexpress LLC L-Glutamine-N,N2-15N2 | 204451-48-9 | 148.13 | 25 MG
L-Glutamine-15N2 is the 15N-labeled version of L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid that is abundant throughout the body and involved in many metabolic processes, providing a source of carbons for oxidation in some cells. This product is for research use only and not sold to patients.
- Can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes of nitrogen (15N).
- Purity: 99.10%.
- Documentation: data sheet, certificate of analysis, safety data sheet, and handling instructions are available.
- Available in various in-stock sizes.
Medchemexpress LLC Deoxycholic acid (Standard) | 83-44-3 | 392.57 | 50 MG
Deoxycholic acid (Standard) is an analytical standard intended for research and analytical applications. It is also known as cholanoic acid, a bile acid that is a by-product of intestinal metabolism and activates the G protein-coupled bile acid receptor TGR5.
- Used in qualitative research experiments such as HPLC, GC, and MS.
- Used in quantitative research experiments such as HPLC, GC, and MS.
- Used in methodological research experiments such as HPLC, GC, and MS.
Medchemexpress LLC Folinic acid-d4 calcium hydrate | 58-05-9 | 91.7% | 605.61 | 250 UG
Folinic acid-d4 calcium hydrate, also known as Leucovorin-d4 calcium hydrate, is a deuterated form of Folinic acid. It functions as a biological folic acid and is typically used as a rescue agent to reduce Methotrexate-induced toxicity. Stable heavy isotopes like deuterium are incorporated into drug molecules to serve as tracers for quantitation during drug development, which can also influence pharmacokinetic and metabolic profiles of drugs.
- Functions as a biological folic acid
- Reduces methotrexate-induced toxicity
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS